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红霉素 98%
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- 品 牌：
- 江蓝纯(Gelatins)
- 产品名：红霉素 98%
CAS号：114-07-8
分子式：C37H67NO13
分子量：733.93
Beilstein号：75279
EC号： 204-040-1
MDL号： MFCD00084654
PubChem编号：24894626
属性
溶解性 熔于乙醇、甲醇、丙酮、氯仿、乙腈和乙酸乙酯，中等程度溶于醚、二氯甲烷和乙酸戊酯。难溶于水。微有引湿性，无臭，味苦。遇酸不稳定。水中溶解度:+/- 3 MG/ML。
熔点 138-140°C
密度 1.2000
旋光率 -74 ° (C=2, EtOH)
荧光 否
IC50 否
pK Values 否
描述
别名 红霉素 ;红霉素碱;(-)-Erythromycin ;Abomacetin
产品介绍 Erythromycin is a potent macrolide inhibitor of CYP3A4 with antiinflammatory and prokinetic properties. Macrolides belong to a group of antibiotics that bind to the 50S ribosomal subunit and inhibit protein synthesis. Erythromycin is derived from Streptomyces erythreus and has been shown to inhibit NF-κB transcriptional activation, which leads to the inhibition of cytokine gene expression of IL-8 and lL-6. This mechanism was shown to occur via calcineruin-independent signaling T lymphocytes.
用途 A macrolide antibiotic protein synthesis inhibitor.Erythromycin is an antibiotic produced by growth of certain strains of Streptomyces erythreus. This product is composed largely of erythromycin A with small amounts of erythromycins B and C and is recommended for concentration at 100 mg/L. Concentrations between 50 and 200 mg/L have also proven effective in controlling bacterial growth. Erythromycin has been used as a motilin receptor agonist, to block respiratory glycoconjugate secretion in human airways in vitro, and for selecting plasmid-cured and recombinant lactococcus lactis MG1363 strains.
生化机理 在转肽步骤抑制延长期，靠结合到核糖体上抑制细菌蛋白合成，对细菌诱发红霉素抗性。抗菌谱: 革兰氏阴性和阳性细菌。属大环内酯抗生素（Macrolide antibiotic）
备注 此产品所配溶液37°C只能保存3天，因此其储存溶液必须2-8°C保存.This product is soluble in water at 2 mg/mL, with a 0.067% solution in water yielding a pH of 8.0-10.5. It is also soluble in ethanol at 50 mg/mL, yielding a clear, colorless to faint yellow solution. It is freely soluble in alcohol, acetone, chloroform, acetonitrile and ethyl acetate but forms salts with acids. All solutions should be protected from light.
江西江蓝纯生物试剂有限公司
- 地址：
- 江西省抚州市抚州高新技术产业开发区金柅大道198号科创孵化基地中小创业企业园B2栋二楼
